(Reuters) - U.S. stocks opened slightly lower on Tuesday after China, a main source of global growth, raised interest rates, while Apple shares fell after the stock's weighting in a widely followed index was cut.

Apple Inc (AAPL.O) lost 1 percent to $337.65, but other tech giants, including Microsoft Corp (MSFT.O) and Cisco Systems (CSCO.O), rose.

The Dow Jones industrial average .DJI was down 21.57 points, or 0.17 percent, at 12,378.46. The Standard & Poor's 500 Index .SPX was down 2.43 points, or 0.18 percent, at 1,330.44. The Nasdaq Composite Index.IXIC was down 0.57 points, or 0.02 percent, at 2,788.62.

(Reporting by Ryan Vlastelica; Editing by Kenneth Barry)

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